ALOX5AP 抗体 (AA 94-124)
Quick Overview for ALOX5AP 抗体 (AA 94-124) (ABIN360268)
抗原
See all ALOX5AP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 94-124
-
特异性
-
This antibody recognizes ALOX5AP.
Cellular Localization: Nucleus membrane. Endoplasmic reticulum membrane. -
纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
-
免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94~124 amino acids selected from the Center region of Human ALOX5AP. Genename: ALOX5AP
-
亚型
- Ig Fraction
-
-
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (C-Term) antibody
Verified ALOX5AP 适用: 人 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) antibodyVerified ALOX5AP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) antibody (Biotin)Verified ALOX5AP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal Biotin
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) antibodyALOX5AP 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) antibodyALOX5AP 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (AA 86-117) antibodyALOX5AP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17169 unconjugated
-
-
应用备注
-
ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
-
别名
- ALOX5AP / FLAP
-
背景
- Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Note=Genetic variations in ALOX5AP may be associated with susceptibility to myocardial infarction. Involvement in myocardial infarction is however unclear: according to some authors (PubMed:14770184), a 4-SNP haplotype in ALOX5AP confers risk of myocardial infarction, while according to other (PubMed:17304054) ALOX5AP is not implicated in this condition. Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.Synonyms: Arachidonate 5-lipoxygenase-activating protein, MK-886-binding protein
-
基因ID
- 241, 9606
-
UniProt
- P20292
抗原
-
