PHLPP2 抗体 (N-Term)
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- 抗原 See all PHLPP2 抗体
- PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHLPP2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to PHLPP2.
- 纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human PHLPP2.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PHLPP2 Primary Antibody
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anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibody
PHLPP2 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (AA 1295-1323), (C-Term) antibodyPHLPP2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB15007 unconjugated
anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2) (C-Term) antibodyVerified PHLPP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
- 别名
- PHLPP2 (PHLPP2 产品)
- 别名
- PHLPPL antibody, phlppl antibody, AI481772 antibody, C130044A18Rik antibody, Phlppl antibody, RGD1562857 antibody, PH domain and leucine rich repeat protein phosphatase 2 antibody, PH domain and leucine rich repeat protein phosphatase 2 S homeolog antibody, PHLPP2 antibody, phlpp2.S antibody, phlpp2 antibody, Phlpp2 antibody
- 背景
- PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.Synonyms: KIAA0931, PH domain leucine-rich repeat-containing protein phosphatase 2, PH domain leucine-rich repeat-containing protein phosphatase-like, PHLPP-like, PHLPPL
- 基因ID
- 23035, 9606
- UniProt
- Q6ZVD8
- 途径
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway
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