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BACE1 抗体 (N-Term)

This anti-BACE1 antibody is a 兔 多克隆 antibody detecting BACE1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN360082
发货至: 中国

Quick Overview for BACE1 抗体 (N-Term) (ABIN360082)

抗原

See all BACE1 抗体
BACE1 (Beta-secretase 1 (BACE1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This BACE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
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    N-Term

    特异性

    This antibody reacts to BACE1.

    纯化方法

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BACE1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/50 - 1/100. Immunohistochemistry on paraffin sections: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    BACE1 (Beta-secretase 1 (BACE1))

    别名

    BACE1

    背景

    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Synonyms: ASP2, Aspartyl protease 2, BACE, BACE-1, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2

    基因ID

    23621, 9606

    UniProt

    P56817
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