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SMAD4 抗体 (Ser277)

The 兔 多克隆 anti-SMAD4 antibody is suitable to detect SMAD4 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN360050
发货至: 中国
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Quick Overview for SMAD4 抗体 (Ser277) (ABIN360050)

抗原

See all SMAD4 抗体
SMAD4 (SMAD Family Member 4 (SMAD4))

适用

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宿主

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克隆类型

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多克隆

标记

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This SMAD4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Ser277

    特异性

    This antibody reacts to SMAD4.

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S277 of human SMAD4.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    SMAD4 (SMAD Family Member 4 (SMAD4))

    别名

    SMAD4

    背景

    SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.Synonyms: DPC4, Deletion target in pancreatic carcinoma 4, MAD homolog 4, MADH4, Mothers against DPP homolog 4, Mothers against decapentaplegic homolog 4, SMAD 4, SMAD family member 4, SMAD-4

    基因ID

    4089, 9606

    UniProt

    Q13485

    途径

    Cell Division Cycle, Chromatin Binding, Autophagy
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