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TEK 抗体 (C-Term)

This anti-TEK antibody is a 兔 多克隆 antibody detecting TEK in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN359945
发货至: 中国

Quick Overview for TEK 抗体 (C-Term) (ABIN359945)

抗原

See all TEK 抗体
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

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宿主

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克隆类型

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多克隆

标记

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This TEK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antiobdy recognizes TEK (TIE2).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human TEK.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    别名

    CD202b / TEK

    背景

    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

    基因ID

    7010, 9606

    UniProt

    Q02763

    途径

    RTK signaling, Growth Factor Binding
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