DCXR 抗体 (Middle Region)
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Quick Overview for DCXR 抗体 (Middle Region) (ABIN359606)
抗原
See all DCXR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody recognizes Human and Mouse DCXR. Other species not tested.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of Human DCXR.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000
Western blotting: 1/50 - 1/100
Immunohistochemistry on Paraffin Sections: 1/50-1/100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
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别名
- L-Xylulose Reductase
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背景
- DCXR is an enzyme that has both diacetyl reductase and L-xylulose reductase activities. Function: Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. Cellular Location: Membrane, Peripheral membrane protein (By similarity). Note=Probably recruited to membranes via an interaction with phosphatidylinositol (By similarity). Tissue Location: Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.Synonyms: Carbonyl reductase II, DCXR, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, P34H, Sperm surface protein P34H, XR
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分子量
- 25913 Da (calculated)
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基因ID
- 51181, 9606
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UniProt
- Q7Z4W1
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途径
- Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process
抗原
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