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VRK1 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects VRK1 in WB 和 EIA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN359566
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VRK1 抗体 (Middle Region) (ABIN359566)

抗原

See all VRK1 抗体
VRK1 (Vaccinia Related Kinase 1 (VRK1))

适用

  • 51
  • 10
  • 2
人, 小鼠

宿主

  • 42
  • 9

克隆类型

  • 44
  • 7
多克隆

标记

  • 26
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VRK1 antibody is un-conjugated

应用范围

  • 43
  • 16
  • 13
  • 13
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    特异性

    This antibody reacts to VRK1.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human VRK1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    VRK1 (Vaccinia Related Kinase 1 (VRK1))

    别名

    VRK1

    背景

    This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.Synonyms: Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1

    基因ID

    7443, 9606

    UniProt

    Q99986
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