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NAE1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects NAE1 in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN359509
发货至: 中国
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Quick Overview for NAE1 抗体 (C-Term) (ABIN359509)

抗原

See all NAE1 抗体
NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

适用

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宿主

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克隆类型

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多克隆

标记

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This NAE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects NAE1 (APPBP1) at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human APPBP1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry on paraffin sections 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

    别名

    APPBP1

    背景

    APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.Synonyms: Amyloid beta precursor protein-binding protein 1, Amyloid protein-binding protein 1, HPP1, NAE1

    分子量

    60252 Da

    基因ID

    8883, 9606

    UniProt

    Q13564
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