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PLK2 抗体 (C-Term)

This anti-PLK2 antibody is a 兔 多克隆 antibody detecting PLK2 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN359469
发货至: 中国

Quick Overview for PLK2 抗体 (C-Term) (ABIN359469)

抗原

See all PLK2 抗体
PLK2 (Polo-Like Kinase 2 (PLK2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 46
多克隆

标记

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This PLK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects PLK2 (SNK) at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SNK.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1-500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PLK2 (Polo-Like Kinase 2 (PLK2))

    别名

    PLK2 / SNK

    背景

    Plks (polo-like kinases) encode serine/threonine kinases that are closelyrelated to polo and CDC5, genes that are required for passage through mitosisin Drosophila and Saccharomyces, respectively. Polo-like kinases, whichinclude Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cellproliferation. Plk protein accumulates in the cell during S and G2 phases ofthe cell cycle, and both protein content and catalytic activity peak at theonset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk areimmediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.Synonyms: PLK-2, Polo-like kinase 2, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase SNK, Serum-inducible kinase

    分子量

    78236 Da

    基因ID

    10769, 9606

    UniProt

    Q9NYY3
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