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DCLK1 抗体 (C-Term)

This anti-DCLK1 antibody is a 兔 多克隆 antibody detecting DCLK1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN359414
发货至: 中国

Quick Overview for DCLK1 抗体 (C-Term) (ABIN359414)

抗原

See all DCLK1 抗体
DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This DCLK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects DCAMKL1 at C-term.

    纯化方法

    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DCAMKL1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

    别名

    Doublecortin-Like Kinase 1

    背景

    Doublecortin-like kinase (DCAMKL1)(Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.Synonyms: CLICK1, DCAMKL1, DCDC3A, DCKL1, DCLK, KIAA0369, Serine/threonine-protein kinase DCLK1

    分子量

    82223 Da

    基因ID

    9201, 9606

    UniProt

    O15075
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