ERN2 抗体 (N-Term)
This anti-ERN2 antibody is a 兔 多克隆 antibody detecting ERN2 in WB 和 EIA. Suitable for 人 和 小鼠.
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Quick Overview for ERN2 抗体 (N-Term) (ABIN359268)
抗原
See all ERN2 抗体
ERN2
(Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This ERN2 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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特异性
- This antibody reacts to ERN2 / IRE2.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ERN2.
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亚型
- Ig Fraction
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anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) antibody
ERN2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) (AA 841-890) antibodyERN2 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
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背景
- ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.Synonyms: Endoplasmic reticulum-to-nucleus signaling 2, Inositol-requiring protein 2, Ire1-beta, Serine/threonine-protein kinase/endoribonuclease IRE2
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基因ID
- 10595, 9606
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UniProt
- Q76MJ5
抗原
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