STRADB 抗体 (C-Term)
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北京 101111
Quick Overview for STRADB 抗体 (C-Term) (ABIN359240)
抗原
See all STRADB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to ALS2CR2.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ALS2CR2.
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亚型
- Ig Fraction
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anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 319-418) antibody
STRADB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (C-Term) antibodyVerified STRADB 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 212-418) antibodySTRADB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 251-350) antibodySTRADB 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 1-95) antibodySTRADB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 200-250) antibodySTRADB 适用: 人, Cow, 犬, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (Intermediate Domain) antibodySTRADB 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (C-Term) antibodySTRADB 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- STRADB (STE20-Related Kinase Adaptor beta (STRADB))
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别名
- STRAD beta / ILPIP
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背景
- ALS2CR2 potentiates the antiapoptotic activity of XIAP by enhancing XIAP-mediated activation of JNK1 (MAPK8) and other JNK family members, but not by modulating XIAP-mediated caspase inhibition. Expression of a catalytically inactive TAK1 (MAP3K7) mutant blocks the XIAP/ALS2CR2 activation of JNK1. In vivo coprecipitation experiments show that both ALS2CR2 and XIAP interact with TAK1 and TRAF6. It has been proposed that XIAP-mediated protection from apoptosis utilizes both a JNK1 activation pathway that involves ALS2CR2 and a caspase inhibition pathway that is independent of ALS2CR2.Synonyms: ALS2CR2, CALS-21, PRO1038, Pseudokinase ALS2CR2, STE20-related kinase adapter protein beta, STRADB
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基因ID
- 55437, 9606
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UniProt
- Q9C0K7
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途径
- AMPK Signaling
抗原
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