ILK 抗体 (C-Term)
Quick Overview for ILK 抗体 (C-Term) (ABIN359168)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to ILK2/ILK1.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ILK2/ILK1.
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亚型
- Ig Fraction
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anti-Integrin-Linked Kinase (ILK) antibody
KO Validated ILK 适用: 人 WB, IHC, IHC (p), IP, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 97-244) antibodyILK 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 341-452) antibodyILK 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 301-400) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-260) antibodyILK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 225-253) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 11-41) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (pThr173) antibodyILK 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-228) antibodyILK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (C-Term) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- Integrin-Linked Protein Kinase
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背景
- Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) is an ankyrin repeat containing 51 kDa receptor-proximate serine-threonine kinase (1), with a reported migration rate of 59K. This 451 amino acid protein interacts with the cytoplasmic domain of the beta-1 integrin subunit and contains sequence motifs found in pleckstrin homology domains capable of interacting with phosphoinositide lipids. ILK is an upstream regulator of Pi(3)K dependant activation of protein kinase B (PKB/AKT) and inhibition of glycogen synthase kinase 3 (GSK-3). ILK2 expression is associated with mediation of cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. ILK2 is overexpressed in some highly invasive tumor cell lines.Synonyms: 59 kDa serine/threonine-protein kinase, ILK, ILK-1, ILK-2, ILK1, ILK2, p59ILK
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基因ID
- 16202
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NCBI登录号
- NP_034692
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UniProt
- O55222
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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