PKC gamma 抗体 (C-Term)
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Quick Overview for PKC gamma 抗体 (C-Term) (ABIN359066)
抗原
See all PKC gamma (PRKCG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to PKC gamma.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PKC.
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亚型
- Ig Fraction
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anti-Protein Kinase C, gamma (PRKCG) (pThr514) antibody
KD Validated PRKCG 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4490 unconjugated Recombinant Antibody
anti-Protein Kinase C, gamma (PRKCG) (pThr514) antibodyPRKCG 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) antibodyPRKCG 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4495 unconjugated Recombinant Antibody
anti-Protein Kinase C, gamma (PRKCG) (AA 260-351) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Internal Region) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Thr655) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 1-314) antibodyPRKCG 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) antibodyPRKCG 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 71-120) antibodyPRKCG 适用: 人, 大鼠, 小鼠, Cow, 兔, 猴, 犬, 豚鼠, 马, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 539-588) antibodyPRKCG 适用: 人, 大鼠, 小鼠, Cow, 兔, 猴, 犬, 豚鼠, 马, 斑马鱼, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
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别名
- PRKCG
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背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC gamma is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).Synonyms: PKC gamma, PKC-gamma, PKCC, PKCG, Protein kinase C gamma type
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基因ID
- 5582, 9606
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UniProt
- P05129
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途径
- WNT signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
抗原
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