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PARK7/DJ1 抗体 (N-Term)

The 兔 多克隆 anti-PARK7/DJ1 antibody is suitable to detect PARK7/DJ1 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN358997
发货至: 中国
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Quick Overview for PARK7/DJ1 抗体 (N-Term) (ABIN358997)

抗原

See all PARK7/DJ1 (PARK7) 抗体
PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

适用

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宿主

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克隆类型

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多克隆

标记

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This PARK7/DJ1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to PARK7 (DJ-1).

    纯化方法

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Park7 (DJ-1).

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

    别名

    DJ-1 / PARK7

    背景

    Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa.Synonyms: Oncogene DJ1, Parkinson disease protein 7

    基因ID

    11315, 9606

    UniProt

    Q99497

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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