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ZBTB7B 抗体 (Middle Region)

This anti-ZBTB7B antibody is a 兔 多克隆 antibody detecting ZBTB7B in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN358973
发货至: 中国

Quick Overview for ZBTB7B 抗体 (Middle Region) (ABIN358973)

抗原

See all ZBTB7B 抗体
ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

适用

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人, 小鼠

宿主

  • 23
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克隆类型

  • 25
  • 6
多克隆

标记

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This ZBTB7B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Middle Region

    特异性

    This antibody reacts to ZBTB7B.

    纯化方法

    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZBTB7B.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

    别名

    ZBTB7B

    背景

    ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.Synonyms: T-helper-inducing POZ/Krueppel-like factor, Th-POK, Thpok, ZBT-15, ZBTB15, ZFP67, Zfp-67, Zinc finger and BTB domain-containing protein 15, Zinc finger and BTB domain-containing protein 7B, Zinc finger protein 67 homolog, c-Krox, cKrox

    基因ID

    51043, 9606

    UniProt

    O15156
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