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Sclerostin 抗体 (Middle Region)

This anti-Sclerostin antibody is a 兔 多克隆 antibody detecting Sclerostin in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN358752
发货至: 中国
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Quick Overview for Sclerostin 抗体 (Middle Region) (ABIN358752)

抗原

See all Sclerostin (SOST) 抗体
Sclerostin (SOST)

适用

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宿主

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克隆类型

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  • 9
多克隆

标记

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This Sclerostin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 141-171, Middle Region

    特异性

    This antibody recognizes SOST (Center).

    纯化方法

    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide between 141~171 amino acids from the Center region of Human SOST.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50-1/100Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Sclerostin (SOST)

    别名

    Sclerostin / SOST

    背景

    Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

    基因ID

    50964, 9606

    UniProt

    Q9BQB4
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