Sclerostin 抗体 (Middle Region)
Quick Overview for Sclerostin 抗体 (Middle Region) (ABIN358752)
抗原
See all Sclerostin (SOST) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-171, Middle Region
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特异性
- This antibody recognizes SOST (Center).
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纯化方法
- Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 141~171 amino acids from the Center region of Human SOST.
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亚型
- Ig Fraction
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anti-Sclerostin (SOST) (AA 12-42), (N-Term) antibody
SOST 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12388 unconjugated
anti-Sclerostin (SOST) (AA 25-213) antibodySOST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 24-213) antibodySOST 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 24-213) antibodySOST 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 121-180) antibodySOST 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, ICC, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (N-Term) antibodySOST 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 25-209) antibodySOST 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 38-87) antibodySOST 适用: 人, 犬, Pig, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (C-Term) antibodyVerified SOST 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 134-163) antibodySOST 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13011 unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/50-1/100Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Sclerostin (SOST)
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别名
- Sclerostin / SOST
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背景
- Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
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基因ID
- 50964, 9606
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UniProt
- Q9BQB4
抗原
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