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WISP3 抗体 (Middle Region)

This anti-WISP3 antibody is a 兔 多克隆 antibody detecting WISP3 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN358747
发货至: 中国

Quick Overview for WISP3 抗体 (Middle Region) (ABIN358747)

抗原

See all WISP3 抗体
WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

适用

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宿主

  • 39
  • 1

克隆类型

  • 40
多克隆

标记

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This WISP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 7
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    • 1
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    Middle Region

    特异性

    This antibody reacts to WISP3.

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    KLH conjugated synthetic peptide selected from the center region of human WISP3

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50 - 1/200. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

    别名

    WISP3

    背景

    WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis.Synonyms: CCN6, UNQ462/PRO790/PRO956, WISP-3, WNT1-inducible-signaling pathway protein 3

    基因ID

    8838, 9606

    UniProt

    O95389

    途径

    WNT signaling, Growth Factor Binding
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