WISP3 抗体 (Middle Region)
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Quick Overview for WISP3 抗体 (Middle Region) (ABIN358747)
抗原
See all WISP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody reacts to WISP3.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- KLH conjugated synthetic peptide selected from the center region of human WISP3
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western Blot: 1/50 - 1/200. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
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别名
- WISP3
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背景
- WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis.Synonyms: CCN6, UNQ462/PRO790/PRO956, WISP-3, WNT1-inducible-signaling pathway protein 3
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基因ID
- 8838, 9606
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UniProt
- O95389
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途径
- WNT signaling, Growth Factor Binding
抗原
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