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WISP2 抗体 (Middle Region)

WISP2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358746
发货至: 中国
  • 抗原 See all WISP2 抗体
    WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
    抗原表位
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 42
    • 6
    • 4
    • 1
    • 1
    • 1
    宿主
    • 36
    • 8
    克隆类型
    • 37
    • 7
    多克隆
    标记
    • 27
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WISP2 antibody is un-conjugated
    应用范围
    • 32
    • 19
    • 11
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to WISP2.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human WISP2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product WISP2 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
    别名
    WISP2 (WISP2 产品)
    别名
    MGC84196 antibody, WISP2 antibody, ccn5 antibody, CCN5 antibody, CT58 antibody, CTGF-L antibody, Ccn5 antibody, Crgr4 antibody, Ctgfl antibody, Rcop1 antibody, WNT1 inducible signaling pathway protein 2 antibody, WNT1 inducible signaling pathway protein 2 S homeolog antibody, WISP2 antibody, wisp2.S antibody, wisp2 antibody, Wisp2 antibody
    背景
    Wisp2 a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. Wisp2 lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.Synonyms: CCN5, CT58, CTGF-L, CTGFL, Connective tissue growth factor-like protein, Connective tissue growth factor-related protein 58, UNQ228/PRO261, WISP-2, WNT1-inducible-signaling pathway protein 2
    基因ID
    8839
    NCBI登录号
    NP_003872
    UniProt
    O76076
    途径
    WNT signaling, Growth Factor Binding
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