WISP1 抗体 (Middle Region)
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- 抗原 See all WISP1 抗体
- WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WISP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to WISP1.
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human WISP1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product WISP1 Primary Antibody
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anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibody
Verified WISP1 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 213-350) antibodyWISP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 130-251) antibodyWISP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 354-367), (C-Term) antibodyWISP1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 1-280) antibodyWISP1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 237-295) antibodyWISP1 适用: 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 216-347) antibodyWISP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibodyWISP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 158-367) antibodyWISP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 216-347) antibodyWISP1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
- 别名
- WISP1 (WISP1 产品)
- 别名
- CCN4 antibody, WISP1c antibody, WISP1i antibody, WISP1tc antibody, WISP-1 antibody, WISP1 antibody, si:ch211-38f10.2 antibody, AW146261 antibody, Elm1 antibody, zgc:172276 antibody, WNT1 inducible signaling pathway protein 1 antibody, WNT1 inducible signaling pathway protein 1a antibody, WNT1-inducible-signaling pathway protein 1-like antibody, WNT1 inducible signaling pathway protein 1b antibody, WISP1 antibody, wisp1a antibody, Wisp1 antibody, LOC100627044 antibody, wisp1b antibody
- 背景
- Wisp1 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. Wisp1 may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83 % identical to the mouse protein at the amino acid level.Synonyms: CCN family member 4, CCN4, WNT1-inducible-signaling pathway protein 1, Wnt-1-induced secreted protein
- 基因ID
- 8840
- NCBI登录号
- NP_001191798
- UniProt
- O95388
- 途径
- WNT signaling, Growth Factor Binding
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