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XIAP 抗体 (N-Term)

This anti-XIAP antibody is a 兔 多克隆 antibody detecting XIAP in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN358604
发货至: 中国

Quick Overview for XIAP 抗体 (N-Term) (ABIN358604)

抗原

See all XIAP 抗体
XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This XIAP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to XIAP (BIRC4).

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BIRC4.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

    别名

    IAP3 / BIRC4

    背景

    BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.Synonyms: API3, Baculoviral IAP repeat-containing protein 4, E3 ubiquitin-protein ligase XIAP, HILP, Inhibitor of apoptosis protein 3, X-linked IAP, X-linked inhibitor of apoptosis protein, XIAP

    基因ID

    331, 9606

    UniProt

    P98170

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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