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SMAD4 抗体 (pThr277)

SMAD4 适用: 人 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358227
发货至: 中国
  • 抗原 See all SMAD4 抗体
    SMAD4 (SMAD Family Member 4 (SMAD4))
    抗原表位
    • 12
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr277
    适用
    • 100
    • 42
    • 37
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 89
    • 11
    • 1
    克隆类型
    • 75
    • 26
    多克隆
    标记
    • 57
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD4 antibody is un-conjugated
    应用范围
    • 67
    • 46
    • 36
    • 30
    • 22
    • 12
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SMAD4 pThr277.
    交叉反应 (详细)
    Species reactivity (expected):Mouse (100 % Antigen Homology).
    Species reactivity (tested):Human.
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SMAD4 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    SMAD4 (SMAD Family Member 4 (SMAD4))
    别名
    SMAD4 (SMAD4 产品)
    别名
    smad4 antibody, DPC4 antibody, JIP antibody, MADH4 antibody, MYHRS antibody, AW743858 antibody, D18Wsu70e antibody, Madh4 antibody, XSmad4alpha antibody, Xsmad4 antibody, dpc4 antibody, jip antibody, madh4 antibody, xsmad4a antibody, SMAD family member 4 antibody, Smad4 protein antibody, SMAD family member 4, gene 1 L homeolog antibody, SMAD4 antibody, smad4 antibody, Smad4 antibody, smad4.1.L antibody
    背景
    Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.Synonyms: DPC4, Deletion target in pancreatic carcinoma 4, MAD homolog 4, MADH4, Mothers against DPP homolog 4, Mothers against decapentaplegic homolog 4, SMAD 4, SMAD family member 4, SMAD-4
    分子量
    60439 Da
    基因ID
    4089, 9606
    UniProt
    Q13485
    途径
    Cell Division Cycle, Chromatin Binding, Autophagy
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