DAXX 抗体 (pSer213)
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- 抗原 See all DAXX 抗体
- DAXX (Death-Domain Associated Protein (DAXX))
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抗原表位
- pSer213
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAXX antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects DAXX pSer213.
- 纯化方法
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S213 of human DAXX.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product DAXX Primary Antibody
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anti-Death-Domain Associated Protein (DAXX) (AA 561-660) antibody
DAXX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 558-740) antibodyDAXX 适用: 人 WB, ICC 宿主: 小鼠 Monoclonal DAXX-01 unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 56-345) antibodyDAXX 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (C-Term) antibodyDAXX 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 481-626) antibodyDAXX 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer213) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer495) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 1-740) antibodyDAXX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- DAXX (Death-Domain Associated Protein (DAXX))
- 别名
- DAXX (DAXX 产品)
- 别名
- BING2 antibody, DAP6 antibody, EAP1 antibody, LOC100226911 antibody, daxx antibody, si:dz179b20.7 antibody, wu:fd15c03 antibody, death domain associated protein antibody, Fas death domain-associated protein antibody, 28S ribosomal protein S29, mitochondrial antibody, death-domain associated protein antibody, death-associated protein 6 L homeolog antibody, DAXX antibody, Daxx antibody, LOC100226911 antibody, daxx.L antibody, daxx antibody
- 背景
- DAXX is proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. DAXX seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. This protein down-regulates basal and activated transcription, and it also seems to act as a transcriptional co-repressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. DAXX modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein
- 分子量
- 81373 Da
- 基因ID
- 1616, 9606
- UniProt
- Q9UER7
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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