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ABL2 抗体 (Middle Region)

This anti-ABL2 antibody is a 兔 多克隆 antibody detecting ABL2 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN358072
发货至: 中国

Quick Overview for ABL2 抗体 (Middle Region) (ABIN358072)

抗原

See all ABL2 抗体
ABL2

适用

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宿主

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克隆类型

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多克隆

标记

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This ABL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    Middle Region

    特异性

    This antibody detects ABL2 (Center) Predicted to cross react with Mouse (100 % Antigen Homology).

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human ABL2.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    ABL2

    别名

    ABL2

    背景

    ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. It is involved in translocation with the ETV6 gene in human leukemia and has an altered expression in several human carcinomas. Two isoforms of ABL2 with different N-termini (1A and 1B) have been identified. The C-terminal domain of ABL2 contains two F-actin-binding sequences that perform a number of actions related to cell morphology and motility by interacting with actin filaments.Synonyms: ABLL, ARG, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine kinase ARG, Tyrosine-protein kinase ABL2

    分子量

    128343 Da

    基因ID

    27, 9606

    UniProt

    P42684
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