Ataxin 1 抗体
Quick Overview for Ataxin 1 抗体 (ABIN357975)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Ataxin-1 (ATXN1).
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纯化方法
- Protein A Chromatography followed by peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S776 of human ATXN1.
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亚型
- Ig Fraction
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anti-Ataxin 1 (ATXN1) (AA 645-815) antibody
ATXN1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4C7B11 unconjugated
anti-Ataxin 1 (ATXN1) antibodyATXN1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Ataxin 1 (ATXN1) (AA 645-815) antibodyATXN1 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B8A2 unconjugated
anti-Ataxin 1 (ATXN1) (AA 569-807) antibodyATXN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (C-Term) antibodyATXN1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 331-587) antibodyATXN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 346-475) antibodyATXN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 746-761) antibodyATXN1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S65-37 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibodyATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibody (HRP)ATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 HRP
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应用备注
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ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Ataxin 1 (ATXN1)
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别名
- Ataxin-1
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背景
- The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known.Synonyms: ATX1, ATXN1, Ataxin 1, SCA1, Spinocerebellar ataxia type 1 protein
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分子量
- 86923 Da
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基因ID
- 6310, 9606
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UniProt
- P54253
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途径
- Synaptic Membrane
抗原
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