Cadherin 5 抗体 (N-Term)
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Quick Overview for Cadherin 5 抗体 (N-Term) (ABIN357862)
抗原
See all Cadherin 5 (CDH5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects VE Cadherin (CD144/CDH5) (N-term).
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纯化方法
- Protein A Chromatography followed by peptide affinity purification
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the N-term of human CDH5.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Cadherin 5 (CDH5)
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别名
- CD144 / Cadherin-5
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背景
- CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.Synonyms: 7B4 antigen, CDH5, VE-Cadherin, Vascular endothelial cadherin
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分子量
- 87516 Da
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基因ID
- 1003, 9606
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UniProt
- P33151
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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