ACSL4 抗体 (AA 244-274)
Our Local Distributor
北京 101111
Quick Overview for ACSL4 抗体 (AA 244-274) (ABIN357780)
抗原
See all ACSL4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 244-274
-
特异性
- This antibody is specific to ACSL4/FACL4 (Center).
-
纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
-
免疫原
- KLH conjugated synthetic peptide between 244~274 amino acids from the center region of human FACL4.
-
亚型
- Ig Fraction
-
-
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (AA 1-280) antibody
ACSL4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (C-Term) antibodyACSL4 适用: 人 WB, IF, ICC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) antibodyKD Validated ACSL4 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2960 unconjugated Recombinant Antibody
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (C-Term) antibodyVerified ACSL4 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (AA 457-670) antibodyACSL4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) antibodyACSL4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (N-Term) antibodyACSL4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (AA 236-267) antibodyACSL4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04697 unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (N-Term) antibodyACSL4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) (AA 236-267) antibodyACSL4 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))
-
别名
- ACSL4
-
背景
- Long chain acyl-CoA synthetase (LACS), or long chain fatty acid-CoA ligase (FACL), converts free long chain fatty acids into fatty acyl-CoA esters, key intermediates in the synthesis of complex lipids. The FACL4 gene encodes a form of LACS and is expressed in several tissues, including brain. FACL4 cDNA from brain encodes a gene product that shows preference for arachidonic acid as a substrate when expressed in mammalian cells.1 The sequence of the predicted 670-amino acid human protein is 97 % identical to that of rat ACS4. FACL4 is highly expressed in adult human brain, especially in the cerebellum and hippocampus, similar to the mouse.2 A strong cytoplasmic staining was found in the Purkinje and granular cells of the cerebellum and the pyramidal layer of hippocampus, indicating that FACL4 is specifically expressed in neurons and not in glial cells. Two patients with Alport syndrome, elliptocytosis, and mental retardation carried a large deletion of the COL4A5 region that included FACL4.3 The absence of FACL4 might play a role in the development of mental retardation or other signs associated with Alport syndrome. Two point mutations, 1 missense and 1 splice site change, were reported in the FACL4 gene in 2 families with nonspecific mental retardation.2 Analysis of enzymatic activity in lymphoblastoid cell lines of affected individuals revealed low levels compared with normal cells, indicating that both mutations are null mutations.Synonyms: ACS4, FACL4, LACS4, Long-chain acyl-CoA synthetase 4, Long-chain-fatty-acid--CoA ligase 4
-
分子量
- 79188 Da
-
基因ID
- 2182, 5874
-
UniProt
- O60488
抗原
-
