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HSF1 抗体 (Sumoylation Site)

This anti-HSF1 antibody is a 兔 多克隆 antibody detecting HSF1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN357730
发货至: 中国

Quick Overview for HSF1 抗体 (Sumoylation Site) (ABIN357730)

抗原

See all HSF1 抗体
HSF1 (Heat Shock Factor Protein 1 (HSF1))

适用

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宿主

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克隆类型

  • 120
  • 60
多克隆

标记

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This HSF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Sumoylation Site

    特异性

    This antibody detects HSF1 Sumoylation Site.

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with the KLH conjugated synthetic peptide PLVRVKEEPPSPPQSPR containing a predicted sumoylation site from the central region of human HSF1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    HSF1 (Heat Shock Factor Protein 1 (HSF1))

    别名

    Heat Shock Factor 1 / HSF1

    背景

    Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.Synonyms: HSF-1, HSTF1, Heat shock transcription factor 1

    分子量

    57260 Da

    基因ID

    3297, 9606

    UniProt

    Q00613
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