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GGPS1 抗体 (C-Term)

This anti-GGPS1 antibody is a 兔 多克隆 antibody detecting GGPS1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357716
发货至: 中国

Quick Overview for GGPS1 抗体 (C-Term) (ABIN357716)

抗原

See all GGPS1 抗体
GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GGPS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects GGPS1 (C-term).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GGPS1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

    别名

    GGPP Synthetase

    背景

    Geranylgeranyl diphosphate (GGPP) synthase (GGPS) catalyzes the synthesis of GGPP, a molecule responsible for the C20-prenylation of protein and for the regulation of a nuclear hormone receptor. The deduced 300-amino acid human protein contains 5 conserved domains consistent with prenyltransferases. Recombinant GGPS shows enzymatic properties associated with the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. Mouse GGPS is regulated in several tissues in obesity and is induced during adipocyte differentiation. GGPS is increased 5- to 20-fold in skeletal muscle, liver, and fat of ob/ob mice. Western blot analysis detects a 2-fold overexpression of protein in muscle and fat but not in liver. Differentiation of mouse fibroblasts into adipocytes induces GGPS expression more than 20-fold.Synonyms: GGPPSase, GGPS1, Geranylgeranyl pyrophosphate synthetase

    分子量

    34871 Da

    基因ID

    9453, 5874

    UniProt

    O95749
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