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GGPS1 抗体 (C-Term)

GGPS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4789 unconjugated
产品编号 ABIN389056
发货至: 中国
  • 抗原 See all GGPS1 抗体
    GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))
    抗原表位
    • 14
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 270-300, C-Term
    适用
    • 73
    • 35
    • 16
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 70
    • 4
    克隆类型
    • 72
    • 2
    多克隆
    标记
    • 31
    • 8
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GGPS1 antibody is un-conjugated
    应用范围
    • 62
    • 38
    • 25
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human GGPS1.
    克隆位点
    RB4789
    亚型
    Ig Fraction
    Top Product
    Discover our top product GGPS1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Jiang, Backlund, Wassif, Yergey, Porter: "Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 7, pp. 1461-75, (2010) (PubMed).

  • 抗原
    GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))
    别名
    GGPS1 (GGPS1 产品)
    别名
    geranylgeranyl pyrophosphate synthase 1 antibody, DDBDRAFT_0192027 antibody, DDBDRAFT_0233098 antibody, DDB_0192027 antibody, DDB_0233098 antibody, GGPPS antibody, GGPPS1 antibody, 1810026C22Rik antibody, 9530089B04Rik antibody, AI843169 antibody, C79210 antibody, Crlf3 antibody, rGGPS1a antibody, rGGPS1a1 antibody, rGGPS1a2 antibody, rGGPS1a3 antibody, fb05f09 antibody, qm antibody, wu:fb05f09 antibody, zgc:101591 antibody, zgc:56514 antibody, geranylgeranyl pyrophosphate synthase 1 antibody, geranylgeranyl pyrophosphate synthetase antibody, geranyl pyrophosphate synthase antibody, geranylgeranyl pyrophosphate synthase,chloroplastic antibody, geranylgeranyl diphosphate synthase 1 antibody, geranylgeranyl diphosphate synthase 1 L homeolog antibody, GGPS1 antibody, gGPS1 antibody, ggps1 antibody, Ggps1 antibody, ggps1.L antibody
    背景
    Geranylgeranyl diphosphate (GGPP) synthase (GGPS) catalyzes the synthesis of GGPP, a molecule responsible for the C20-prenylation of protein and for the regulation of a nuclear hormone receptor. The deduced 300-amino acid human protein contains 5 conserved domains consistent with prenyltransferases. Recombinant GGPS shows enzymatic properties associated with the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. Mouse GGPS is regulated in several tissues in obesity and is induced during adipocyte differentiation. GGPS is increased 5- to 20-fold in skeletal muscle, liver, and fat of ob/ob mice. Western blot analysis detects a 2-fold overexpression of protein in muscle and fat but not in liver. Differentiation of mouse fibroblasts into adipocytes induces GGPS expression more than 20-fold.
    分子量
    34871
    基因ID
    9453
    NCBI登录号
    NP_001032354
    UniProt
    O95749
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