MIB1 抗体 (N-Term)
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Quick Overview for MIB1 抗体 (N-Term) (ABIN357602)
抗原
See all MIB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody is specific to MIB1 (N-term). Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MIB.
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亚型
- Ig Fraction
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anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 6-221) antibody
MIB1 适用: 人, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6A9C9 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 5-332) antibodyMIB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) antibodyKD Validated MIB1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB420 unconjugated Recombinant Antibody
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 13-42), (N-Term) antibodyMIB1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4448 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) antibodyMIB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 560-860) antibodyMIB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) antibodyMIB1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 769-1000) antibodyMIB1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/20-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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别名
- MIB1
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背景
- MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.Synonyms: DAPK-interacting protein 1, DIP1, E3 ubiquitin-protein ligase MIB1, KIAA1323, Mind bomb homolog 1, ZZANK2, Zinc finger ZZ type with ankyrin repeat domain protein 2
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分子量
- 110135 Da
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基因ID
- 57534, 9606
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UniProt
- Q86YT6
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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