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EPS15L1 抗体 (N-Term)

EPS15L1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357580
发货至: 中国
  • 抗原 See all EPS15L1 products
    EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))
    抗原表位
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 28
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 28
    克隆类型
    • 27
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPS15L1 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to EPS15L1/EPS15R (N-term).
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EPS15R.
    亚型
    Ig Fraction
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))
    别名
    EPS15L1 / EPS15R (EPS15L1 产品)
    背景
    Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP-dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions.Synonyms: Epidermal growth factor receptor substrate 15-like 1, Eps15-related protein
    分子量
    94254 Da
    基因ID
    58513, 9606
    UniProt
    Q9UBC2
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