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USP11 抗体 (N-Term)

USP11 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357538
发货至: 中国
  • 抗原 See all USP11 抗体
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    抗原表位
    • 17
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 57
    • 13
    • 12
    • 1
    • 1
    宿主
    • 51
    • 6
    • 1
    克隆类型
    • 42
    • 16
    多克隆
    标记
    • 29
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This USP11 antibody is un-conjugated
    应用范围
    • 37
    • 28
    • 22
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to USP11 (N-term).
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human USP11.
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP11 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    别名
    USP11 (USP11 产品)
    别名
    USP11 antibody, DKFZp459L098 antibody, UHX1 antibody, 6230415D12Rik antibody, mKIAA4085 antibody, Uhx1 antibody, ubiquitin specific peptidase 11 antibody, universal stress protein antibody, USP11 antibody, RR_RS19935 antibody, Usp11 antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 11, UHX1, Ubiquitin carboxyl-terminal hydrolase 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11
    分子量
    105030 Da
    基因ID
    8237, 5874
    UniProt
    P51784
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