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USP11 抗体 (N-Term)

The 小鼠 单克隆 anti-USP11 antibody is suitable to detect USP11 in samples from 人. It has been validated for WB.
产品编号 ABIN4915064
发货至: 中国
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Quick Overview for USP11 抗体 (N-Term) (ABIN4915064)

抗原

See all USP11 抗体
USP11 (Ubiquitin Specific Peptidase 11 (USP11))

适用

  • 60
  • 22
  • 22
  • 1
  • 1

宿主

  • 51
  • 8
  • 1
小鼠

克隆类型

  • 33
  • 27
单克隆

标记

  • 32
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This USP11 antibody is un-conjugated

应用范围

  • 45
  • 18
  • 16
  • 14
  • 14
  • 12
  • 12
  • 3
  • 1
Western Blotting (WB)

克隆位点

2C9
  • 抗原表位

    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 32-300, N-Term

    原理

    USP11 (2C9) Monoclonal Antibody

    交叉反应

    纯化方法

    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11.

    亚型

    IgG1
  • 应用备注

    WB(1:300-5000)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin, Sodium azide

    注意事项

    This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    USP11 (Ubiquitin Specific Peptidase 11 (USP11))

    别名

    USP11

    背景

    Synonyms: UHX1, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11, USP11

    Background: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome (PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro) (PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, PubMed:20233726).

    基因ID

    8237

    UniProt

    P51784
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