USP4 抗体 (C-Term)
Quick Overview for USP4 抗体 (C-Term) (ABIN357526)
抗原
See all USP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is specific to USP4 (C-term).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human USP4.
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亚型
- Ig Fraction
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anti-Ubiquitin Specific Peptidase 4 (USP4) (AA 632-810) antibody
USP4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 4 (USP4) (Center) antibodyUSP4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 4 (USP4) (Internal Region) antibodyUSP4 适用: 人, 犬, Pig, 兔, 马, Cow, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 4 (USP4) (N-Term) antibodyUSP4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 4 (USP4) (AA 676-773) antibodyUSP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E12 unconjugated
anti-Ubiquitin Specific Peptidase 4 (USP4) (AA 903-933), (C-Term) antibodyUSP4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4269 unconjugated
anti-Ubiquitin Specific Peptidase 4 (USP4) (N-Term) antibodyVerified USP4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 4 (USP4) antibodyUSP4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- USP4 (Ubiquitin Specific Peptidase 4 (USP4))
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别名
- USP4 / UNP
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背景
- Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 4, UNPH, Ubiquitin carboxyl-terminal hydrolase 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Ubiquitous nuclear protein homolog
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分子量
- 108564 Da
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基因ID
- 7375, 5874
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UniProt
- Q13107
抗原
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