NEUROD1 抗体 (C-Term)
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北京 101111
Quick Overview for NEUROD1 抗体 (C-Term) (ABIN357406)
抗原
See all NEUROD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects NeuroD1 at C-term.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NeuroD1 protein.
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亚型
- Ig Fraction
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应用备注
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ELISA 1: 1,000. Western blot 1: 1,000. Immunoprecipitation 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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别名
- NEUROD1
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背景
- NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.Synonyms: NEUROD, NEUROD1, Neurogenic differentiation factor 1
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分子量
- 39890 Da
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基因ID
- 4760, 9606
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UniProt
- Q13562
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途径
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
抗原
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