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NEUROD1 抗体 (C-Term)

This anti-NEUROD1 antibody is a 兔 多克隆 antibody detecting NEUROD1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357406
发货至: 中国
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Quick Overview for NEUROD1 抗体 (C-Term) (ABIN357406)

抗原

See all NEUROD1 抗体
NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

适用

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人, 小鼠

宿主

  • 102
  • 11
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克隆类型

  • 84
  • 31
多克隆

标记

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This NEUROD1 antibody is un-conjugated

应用范围

  • 90
  • 46
  • 26
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  • 1
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 23
    • 16
    • 9
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    • 6
    • 3
    • 3
    • 1
    • 1
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    C-Term

    特异性

    This antibody detects NeuroD1 at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NeuroD1 protein.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 1,000. Immunoprecipitation 1: 1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

    别名

    NEUROD1

    背景

    NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.Synonyms: NEUROD, NEUROD1, Neurogenic differentiation factor 1

    分子量

    39890 Da

    基因ID

    4760, 9606

    UniProt

    Q13562

    途径

    Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
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