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ASCL1 抗体 (C-Term)

ASCL1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357401
发货至: 中国
  • 抗原 See all ASCL1 抗体
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    抗原表位
    • 15
    • 14
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 78
    • 42
    • 27
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 小鼠
    宿主
    • 78
    • 5
    • 2
    克隆类型
    • 80
    • 5
    多克隆
    标记
    • 38
    • 10
    • 8
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCL1 antibody is un-conjugated
    应用范围
    • 72
    • 55
    • 23
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ASCL1 (Achaete-scute homolog 1) at C-term.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human Hash1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ASCL1 Primary Antibody
  • 应用备注
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    别名
    ASCL1 (ASCL1 产品)
    别名
    ASH1 antibody, HASH1 antibody, MASH1 antibody, bHLHa46 antibody, AI225900 antibody, Mash1 antibody, ASCL1 antibody, Zash-1a antibody, ash antibody, asha antibody, id:ibd5085 antibody, im:7138587 antibody, si:dkey-264k15.2 antibody, zash1a antibody, zasha antibody, Xash1 antibody, ascl1-A antibody, Zash-1b antibody, ashb antibody, zashb antibody, achaete-scute family bHLH transcription factor 1 antibody, achaete-scute family bHLH transcription factor 1a antibody, achaete-scute family bHLH transcription factor 1 L homeolog antibody, achaete-scute complex homolog 1 antibody, achaete-scute family bHLH transcription factor 1b antibody, ASCL1 antibody, Ascl1 antibody, ascl1a antibody, ascl1.L antibody, LOC100220505 antibody, ascl1b antibody
    背景
    ACSL1, alternatively titled Hash1 or Mash1, is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. ACSL1 plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. The protein is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests it may also play a role in tumor formation.Synonyms: ASH1, Achaete-scute homolog 1, HASH1, MASH1
    分子量
    25454 Da
    基因ID
    429
    NCBI登录号
    NP_004307
    UniProt
    P50553
    途径
    Dopaminergic Neurogenesis
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