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LYVE1 抗体 (N-Term)

This anti-LYVE1 antibody is a 兔 多克隆 antibody detecting LYVE1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357391
发货至: 中国

Quick Overview for LYVE1 抗体 (N-Term) (ABIN357391)

抗原

See all LYVE1 抗体
LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

适用

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人, 小鼠

宿主

  • 85
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  • 1

克隆类型

  • 82
  • 16
多克隆

标记

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This LYVE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects XLKD1/LYVE1 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human and Mouse.

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human XLKD1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

    别名

    LYVE-1

    背景

    One of the key groups of molecules regulating leukocyte and tumour cell migration is the glycosaminoglycan hyaluronan (HA). In inflammation, the exit of leukocytes across vascular endothelium to the underlying tissues involves interactions with cell surface lectin-like receptors on the leukocytes that bind HA on the lumenal surface of the endothelium. During normal tissue homeostasis and after tissue injury, HA is mobilized from these sites through lymphatic vessels to the lymph nodes where it is degraded before entering the circulation for rapid uptake by the liver. Lymphatic vessel endothelial hyaluronan receptor (LYVE)-1 is a major receptor for HA on the lymph vessel wall. LYVE-1 is expressed primarily on lymphatic vessel endothelium and is likely to be involved in regulating the traffic of leucocytes and tumour cells to lymph nodes.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1

    分子量

    35213 Da

    基因ID

    10894

    NCBI登录号

    NP_006682

    UniProt

    Q9Y5Y7

    途径

    Glycosaminoglycan Metabolic Process
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