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SKP1 抗体 (Middle Region)

This anti-SKP1 antibody is a 兔 多克隆 antibody detecting SKP1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357264
发货至: 中国

Quick Overview for SKP1 抗体 (Middle Region) (ABIN357264)

抗原

See all SKP1 抗体
SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SKP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Middle Region

    特异性

    This antibody detects SKP1 at center.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human SKP1A.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

    别名

    SKP1 / OCP2

    背景

    SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.Synonyms: Cyclin A/CDK2-associated protein p19, EMC19, OCP-2, OCP-II, Organ of Corti protein 2, RNA polymerase II elongation factor-like protein, S-phase kinase-associated protein 1, SKP1A, TCEB1L, Transcription elongation factor B, p19A, p19skp1

    分子量

    18527 Da

    基因ID

    6500, 9606

    UniProt

    P63208

    途径

    Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
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