RENT1/UPF1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for RENT1/UPF1 抗体 (N-Term) (ABIN357204)
抗原
See all RENT1/UPF1 (UPF1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody detects RENT1 at N-term.
-
纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
-
免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RENT1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
ELISA 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
-
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
-
别名
- UPF1 / RENT1
-
背景
- RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.Synonyms: ATP-dependent helicase RENT1, KIAA0221, NORF1, Nonsense mRNA reducing factor 1, Regulator of nonsense transcripts 1, Up-frameshift suppressor 1 homolog
-
分子量
- 124345 Da
-
基因ID
- 5976, 9606
-
UniProt
- Q92900
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-