STAT5B 抗体 (C-Term)
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- 抗原 See all STAT5B 抗体
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAT5B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects STAT5b at C-term.
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human STAT5b.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product STAT5B Primary Antibody
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anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-390) antibody
STAT5B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 678-787) antibodySTAT5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-390) antibodySTAT5B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 40-280) antibodySTAT5B 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 40-280) antibodySTAT5B 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (pSer731) antibodySTAT5B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (N-Term) antibodySTAT5B 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 180-229) antibodySTAT5B 适用: 人, Cow, 犬, 马, Pig, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) antibodyKO Validated STAT5B 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (N-Term) antibodySTAT5B 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 斑马鱼, 豚鼠, 绵羊, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100,
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
- 别名
- STAT5B (STAT5B 产品)
- 别名
- STAT5 antibody, stat5 antibody, STAT5A antibody, STAT5B antibody, signal transducer and activator of transcription 5B antibody, signal transducer and activator of transcription 5B S homeolog antibody, Signal transducer and activator of transcription 5B antibody, STAT5B antibody, Stat5b antibody, stat5b.S antibody, LOC490969 antibody, sta5b antibody, LOC100566752 antibody, LOC100052954 antibody
- 背景
- STAT5b is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.Synonyms: STAT-5B, Signal transducer and activator of transcription 5B
- 分子量
- 89865 Da
- 基因ID
- 6777, 9606
- UniProt
- P51692
- 途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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