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KREMEN1 抗体 (N-Term)

This anti-KREMEN1 antibody is a 兔 多克隆 antibody detecting KREMEN1 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN357077
发货至: 中国

Quick Overview for KREMEN1 抗体 (N-Term) (ABIN357077)

抗原

See all KREMEN1 抗体
KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

适用

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宿主

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克隆类型

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多克隆

标记

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This KREMEN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects Kremen at N-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Kremen.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

    别名

    Kremen Protein 1

    背景

    Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.Synonyms: Dickkopf receptor, KREMEN, KREMEN1, KRM1, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose

    分子量

    63,201 Da

    基因ID

    83999

    NCBI登录号

    NP_001034659

    UniProt

    Q96MU8

    途径

    WNT signaling
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