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TLR6 抗体 (N-Term)

This anti-TLR6 antibody is a 兔 多克隆 antibody detecting TLR6 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357054
发货至: 中国

Quick Overview for TLR6 抗体 (N-Term) (ABIN357054)

抗原

See all TLR6 抗体
TLR6 (Toll-Like Receptor 6 (TLR6))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TLR6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects TLR6 at N-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of mouse TLR6.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100. Western blot 1: 200 - 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TLR6 (Toll-Like Receptor 6 (TLR6))

    别名

    CD286 / TLR6

    背景

    TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.Synonyms: Toll-like receptor 6

    基因ID

    21899, 10090

    UniProt

    Q9EPW9

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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