TLR5 抗体 (N-Term)
Quick Overview for TLR5 抗体 (N-Term) (ABIN357051)
抗原
See all TLR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects TLR5 at N-term.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of mouse TLR5.
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亚型
- Ig Fraction
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anti-Toll-Like Receptor 5 (TLR5) (AA 325-644) antibody
TLR5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 303-514) antibodyTLR5 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 8-1# unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 682-850) antibodyTLR5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 700-800) antibodyTLR5 适用: 人, 小鼠 WB, IHC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 19D759-2 unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 701-810) antibodyTLR5 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 46-205) antibodyTLR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 300-350) antibodyTLR5 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 517-634) antibodyTLR5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated
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应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- TLR5 (Toll-Like Receptor 5 (TLR5))
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别名
- TLR5
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背景
- TLR5, a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents. It also plays a role in mediating detection of bacterial flagellins. TLR5 acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein binds to TIRAP and MyD88 via their respective TIR domains TLR5 is highly expressed in liver, and is detected in lung and at very low levels in most other tissues. The TLR5 gene lies in a locus that is associated with susceptibility to Salmonella. Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA). The strain MOLF/Ei is highly susceptible to the infection, has an unique TLR5 haplotype and a lower expression of TRL5.Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
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分子量
- 97626 Da
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基因ID
- 7100, 10090
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UniProt
- O60602
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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