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Nanog 抗体 (N-Term)

NANOG 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357014
发货至: 中国
  • 抗原 See all Nanog (NANOG) 抗体
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    抗原表位
    • 16
    • 16
    • 12
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-54, N-Term
    适用
    • 132
    • 59
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 122
    • 15
    • 3
    • 1
    克隆类型
    • 117
    • 24
    多克隆
    标记
    • 76
    • 9
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This Nanog antibody is un-conjugated
    应用范围
    • 110
    • 60
    • 43
    • 42
    • 26
    • 26
    • 19
    • 18
    • 18
    • 16
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects NANOG at N-term.
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    KLH conjugated synthetic peptide between 25~54 amino acids from the N-terminal region of Human NANOG.
    亚型
    Ig Fraction
    Top Product
    Discover our top product NANOG Primary Antibody
  • 应用备注
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    别名
    NANOG (NANOG 产品)
    别名
    2410002E02Rik antibody, ENK antibody, ecat4 antibody, NANOG antibody, hacp antibody, wu:fd19e04 antibody, wu:fd20a07 antibody, zgc:193933 antibody, Nanog homeobox antibody, nanog homeobox antibody, Nanog antibody, NANOG antibody, nanog antibody
    背景
    NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.Synonyms: Homeobox protein NANOG
    分子量
    34489 Da
    基因ID
    79923, 9606
    UniProt
    Q9H9S0
    途径
    Stem Cell Maintenance
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