LIN28B 抗体 (Center)
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北京 101111
Quick Overview for LIN28B 抗体 (Center) (ABIN357013)
抗原
See all LIN28B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects LIN28B at center.
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- KLH conjugated synthetic peptide selected from the Center region of human LIN28B
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亚型
- Ig Fraction
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anti-Lin-28 Homolog B (LIN28B) (AA 95-128) antibody
LIN28B 适用: 人 WB, ELISA, FACS, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 1-30) antibodyLIN28B 适用: 人 WB, ELISA, FACS, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 166-250) antibodyLIN28B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) antibodyLIN28B 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 218-250) antibodyLIN28B 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 95-128) antibodyLIN28B 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) antibodyLIN28B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 200-250) antibodyLIN28B 适用: 人, 猴 IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (N-Term) antibodyLIN28B 适用: 人 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 218-250), (C-Term) antibodyLIN28B 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- LIN28B (Lin-28 Homolog B (LIN28B))
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别名
- LIN28B
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背景
- Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains. Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene. Overexpression of LIN28B was noted in most HCC cell lines and clinical samples. A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver. Although predominantly localized in the cytoplasm, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells. Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation.Synonyms: CSDD2, LIN28B, Lin-28 homolog B
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分子量
- 26953 Da
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基因ID
- 389421, 9606
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UniProt
- Q6ZN17
抗原
-
