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Cadherin 8 抗体 (N-Term)

This anti-Cadherin 8 antibody is a Rabbit Polyclonal antibody detecting Cadherin 8 in WB, IHC (p), EIA. Suitable for Human. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN356866
发货至: 中国

Quick Overview for Cadherin 8 抗体 (N-Term) (ABIN356866)

抗原

See all Cadherin 8 (CDH8) 抗体
Cadherin 8 (CDH8)

适用

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宿主

  • 33
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克隆类型

  • 34
多克隆

标记

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This Cadherin 8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody is specific to CDH8 (N-term).

    纯化方法

    Protein A Chromatography followed by Peptide Affinity purification.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CDH8.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Kher, Sha, Escobar, Andreoli, Wang, Xu, Wandinger-Ness, Bacallao: "Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture." in: American journal of physiology. Cell physiology, Vol. 301, Issue 1, pp. C99-C105, (2011) (PubMed).

  • 抗原

    Cadherin 8 (CDH8)

    别名

    Cadherin-8

    背景

    CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.Synonyms: CDH8

    基因ID

    1006, 9606

    UniProt

    P55286

    途径

    Cell-Cell Junction Organization
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