PIAS4 抗体 (C-Term)
Quick Overview for PIAS4 抗体 (C-Term) (ABIN356771)
抗原
See all PIAS4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is specific to PIASy (C-term).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIASy1.
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亚型
- Ig Fraction
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anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibody
PIAS4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 48-79), (N-Term) antibodyPIAS4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0680 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 66-241) antibodyPIAS4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 1-510) antibodyPIAS4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 44-60) antibodyPIAS4 适用: 人, 猴 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (N-Term) antibodyPIAS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴, Bat, 小鸡, Pig, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 60-260) antibodyPIAS4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 471-499), (C-Term) antibodyPIAS4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00682 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibodyPIAS4 适用: 人, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (N-Term) antibodyPIAS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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别名
- PIAS4
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背景
- PIASy1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway, the wnt pathway and the steroid hormone signaling pathway. PIASy1 is involved in gene silencing, and promotes PARK7 sumoylation.Synonyms: E3 SUMO-protein ligase PIAS4, PIAS-gamma, PIASG, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma
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基因ID
- 51588, 9606
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UniProt
- Q8N2W9
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
抗原
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