MLL/KMT2A 抗体 (C-Term)
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Quick Overview for MLL/KMT2A 抗体 (C-Term) (ABIN356674)
抗原
See all MLL/KMT2A (MLL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is specific to HRX (C-term).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human HRX.
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亚型
- Ig Fraction
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anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibody
MLL 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3751-3968) antibodyMLL 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 10F8D7 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 801-956) antibodyMLL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4A5A12 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 2829-2883) antibodyMLL 适用: 人, 小鼠 WB, ChIP, ICC, ChIP-seq, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3561-3670) antibodyMLL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3879-3908), (C-Term) antibodyMLL 适用: 人 IHC (p), FACS 宿主: 兔 Polyclonal RB02951 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
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别名
- MLL / HRX
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背景
- The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. Tse et al. (1995) characterized 2 t(1,11)(q21,q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21, AF1Q, in 2 infants with acute myelomonocytic leukemia. In one of these patients, the derivative chromosome 11 represented an in-frame fusion of the N-terminal portion of the MLL gene to the complete AF1Q open reading frame, whereas the derivative chromosome 1 did not give rise to an open reading frame. This observation suggested that the N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23.Synonyms: ALL-1, ALL1, CXXC-type zinc finger protein 7, CXXC7, HTRX, Histone-lysine N-methyltransferase HRX, KMT2A, Lysine N-methyltransferase 2A, TRX1, Trithorax-like protein, Zinc finger protein HRX
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基因ID
- 4297, 5874
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UniProt
- Q03164
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途径
- Warburg Effect
抗原
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