DNMT3L 抗体 (AA 392-421)
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Quick Overview for DNMT3L 抗体 (AA 392-421) (ABIN356591)
抗原
See all DNMT3L (TRDMT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 392-421
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特异性
- This antibody is specific to Mouse Dnmt3L. It may recognize the Human homolog (44 kDa)
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交叉反应 (详细)
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Species reactivity (expected):Human.
Species reactivity (tested):Mouse. -
纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 392~421 amino acids from the Mouse Dnmt3L sequence within the last 100 aa.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
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别名
- DNMT3L
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背景
- MDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.Synonyms: DNA (cytosine-5)-methyltransferase 3-like
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基因ID
- 54427, 10090
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UniProt
- Q9CWR8
抗原
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