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DNMT3L 抗体 (AA 392-421)

This anti-DNMT3L antibody is a 兔 多克隆 antibody detecting DNMT3L in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN356591
发货至: 中国

Quick Overview for DNMT3L 抗体 (AA 392-421) (ABIN356591)

抗原

See all DNMT3L (TRDMT1) 抗体
DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

适用

  • 73
  • 18
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人, 小鼠

宿主

  • 69
  • 12

克隆类型

  • 71
  • 10
多克隆

标记

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This DNMT3L antibody is un-conjugated

应用范围

  • 65
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  • 7
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  • 4
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  • 2
  • 1
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
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    AA 392-421

    特异性

    This antibody is specific to Mouse Dnmt3L. It may recognize the Human homolog (44 kDa)

    交叉反应 (详细)

    Species reactivity (expected):Human.
    Species reactivity (tested):Mouse.

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide between 392~421 amino acids from the Mouse Dnmt3L sequence within the last 100 aa.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

    别名

    DNMT3L

    背景

    MDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.Synonyms: DNA (cytosine-5)-methyltransferase 3-like

    基因ID

    54427, 10090

    UniProt

    Q9CWR8
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